Result · Life Foundational math Resolved

Metabolic Network Topology

Why do metabolic networks have hub-and-spoke topology with the Krebs cycle at the center? The τ-framework derives this: the Krebs cycle is the canonical Lo…

Biology Structural support result CELL Book VI

Overview

Why do metabolic networks have hub-and-spoke topology with the Krebs cycle at the center? The τ-framework derives this: the Krebs cycle is the canonical Loop_L instantiation — the minimal Poincaré circulation.

Result Statement

Krebs cycle as canonical Loop_L instantiation. Hub topology follows from Poincaré circulation minimality. Status: Resolved.